đź‘‹ Hi, there! Welcome to the Malacrino Lab!


The Malacrino Lab in the Department of Biological Sciences at Clemson University focuses on fundamental and applied research on microbiomes.

Our research is a blend of theory drawn from evolutionary biology, community ecology, and multitrophic interactions, combined with cutting-edge tools in molecular biology, experimental evolution, high-throughput sequencing, and high-performance computing to delve deep into the mechanisms governing the interplay between hosts and their microbiomes. Our goal is to answer important fundamental questions: how do microbiomes influence host ecology and evolution? Which are the rules behind the assembly of microbial communities? Can we assemble/evolve microbiomes to drive changes in host traits? We mostly focus on soil, plants and their herbivores.

In our quest to uncover the mechanisms and consequences of host-microbiome interactions, we aim to build a diverse and inclusive research group, welcoming great ideas and promoting tolerance and mutual respect.

Research topics

Plant holobionts

Plant holobionts

We study plants as holobionts—integrated systems made up of the plant and its associated microbial partners—to understand how this collective unit responds to environmental challenges and shapes plant health, development, and evolution.

Select and evolve microbiomes to implement novel functional traits

Select and evolve microbiomes to implement novel functional traits

We use experimental evolution to shape microbiomes that enhance specific traits in plants.

Understanding the rules behind plant microbiomes assembly

Understanding the rules behind plant microbiomes assembly

We investigate the ecological and environmental factors that govern how microbial communities assembly on plants.

Do microbes help invasive species?

Do microbes help invasive species?

We explore how microbial partners may contribute to the success of invasive plants and insects in new environments.

Microbiomes influence plant evolution

Microbiomes influence plant evolution

We examine how plant-associated microbes can act as drivers of plant evolution.

Plant-microbiome-insect interactions

Plant-microbiome-insect interactions

We study how microbes influence plant interactions with insects, from pollinators to herbivores, and how insects in turn shape plant microbiomes.